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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

HEC Paris is not ranked first in any of the individual criteria but registered a strong performance throughout. Its alumni have the fifth-highest salaries three years after graduation at $93,000 and the programme is ranked third for value for money and the international mobility of its alumni. The school also shares the highest score — 93 per cent — for aims achieved.
“I don’t think there are any companies that have survived big assaults from two of the biggest beasts in the hedge fund jungle,” says Ms Simpson of Calpers. “He is cool, calm and collected — the corporate exemplar of ‘Keep calm and carry on’.”

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

2.《活力王子》中的王子几乎破产
不过,在长达四小时的马拉松般的颁奖典礼中,《月光男孩》所获奖项一度与《爱乐之城》并驾齐驱。巴里?詹金斯(Barry Jenkins,文首图中)和塔雷尔?阿尔文?麦克拉尼(Tarell Alvin McCraney,文首图右)获得了最佳改编剧本奖。马赫沙拉?阿里(Mahershala Ali)获得最佳男配角奖,这是美国穆斯林男演员首位获得奥斯卡奖。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

1、拖延

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Local residents living near the launch sites have complained that the activists are putting their lives at risk by making them potential targets for North Korean retaliation.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

"China is Australia's most valuable tourism market, with the potential to be worth more than $13 billion by 2020."
科技巨头腾讯创始人马化腾凭借2790亿元的身家位居榜首,阿里巴巴的马云和恒大集团的许家印紧随其后,其个人财富分别为2600亿元和2290亿元。
科学家们让夫妻进入实验室,在他们开始“别扭”对话时观察他们的压力水平。研究发现,面对压力时,用大笑等积极情绪缓解压力的夫妻在一起的时间往往更久。
May your New Year be filled with special moment, warmth, peace and happiness, the joy of covered ones near, and wishing you all the joys of Christmas and a year of happiness.愿你的新年充满温馨,祥和,与亲人团聚的快乐,祝乐陶陶,新年乐无限。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

John Hummel, chief investment officer for AIS Group, a fund manager with $400 million under management, said all the new sources of global oil are expensive to extract, and he sees U.S. shale output falling by 2015.
《灾难艺术家》一部分是关于好朋友的电影。一部分是娱乐业的新片,还有一部分是幕后的电影短片。
Elspeth Cheung, head of BrandZ valuation at Millward Brown, says: “The top 10 used to be dominated by consumer goods. This year, it’s technology.”
Technically it is a project of the 10-member Association of Southeast Asian Nations to bring all of its trade deals in the region under one umbrella. It also lacks the ambition on many fronts of the TPP.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

这部电影有趣、使人着迷,有不少迂回的、令人惊喜的桥段,让你无法预测结局。和很多好莱坞最好的电影一样,这部电影闪耀人性光辉。既契合当下,又经典隽永。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Busting through the glass ceiling

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

但是,只要快速扫一眼日益变化的天际线,我们就能发现一个令人沮丧的现实:那些光鲜亮丽的新大厦,未能提供大部分纽约人买得起的房型。“我们正在修建的房屋,跟我们需要修建的房屋之间存在着脱节,”房地产估值公司米勒·塞缪尔(Miller Samuel)的总裁乔纳森·J·米勒表示,“2015年,这一现象会更加明显。”
"We have a system here in America where if something is for you and if they find it, it gets to you, that's beautiful," he told US TV station WTAE.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

2.这里没有人能够回答你问的任何关于击剑的问题。还是去google一下吧。
6. The 2012 Ig Nobel Prize for Literature

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 保障房里首次有了“暖心驿站”
Open Access Review Article

Diagnostic technologies for COVID-19: a review

肺的一项意外功能被发现了。研究人员发现肺不仅仅能促进呼吸作用,在造血方面也起关键作用,肺每小时能制造1000多万血小板(微小的血细胞),这相当于任何特定时刻循环中的血小板的大多数。
“A worker sent a text to a colleague saying he was quitting and asked her to forward it to management.”

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

据德国工商总会的统计数据显示,中国于2016年超越美国,首次成为德国的最大贸易市场。
卷铺走人的时候
Mr. Sissako is both an indispensable political filmmaker and one of the great poets of contemporary cinema. His portrait of life under jihadi rule in northern Mali is brutal and shocking, but also gentle, generous and surprisingly funny. Mr. Sissako does not humanize violent extremists so much as demonstrate that they already belong to the species and reflect part of our common, tragic nature. But his movie also insists that the only effective and ethically serious way to oppose fanaticism is with humanism. Which is to say with irony, with decency and, perhaps above all, with art. (Read the review.)
马克斯将与她的朋友克洛伊一起,揭开她的同学雷切尔o安布尔神秘失踪背后的真相。游戏具有电影的体验感,配有不拘一格的原声,将当下年轻女孩的焦虑与生死攸关的情境结合了起来,再加上了时光倒流的能力,这一切使得这款游戏脱颖而出。尽管该作品中采用的机制在其他游戏中曾经用过,但由法国开发商制作的美国风格游戏,还是让这种定时操作有耳目一新的感觉。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

因特尔:新员工红地毯

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

“听起来,哈佛对学生的私生活管得太宽了”,曾为OJ?辛普森等多位名人做过代理律师的德肖维茨说。
7. Smart cookie oven

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

The app D'Aloisio designed, Summly, compresses long pieces of text into a few representative sentences. When he released an early iteration, tech observers realized that an app that could deliver brief, accurate summaries would be hugely valuable in a world where we read everything-from news stories to corporate reports-on our phones, on the go. The app attracted the interest of investors around the world, ranging from Hollywood celebrities to Hong Kong billionaire Li Ka-shing, the wealthiest man in Asia.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Comedy Series: “Veep” (HBO)

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

如果美国汽车行业杂志《沃兹汽车》(Wardsauto)的专家最新编撰的最佳引擎榜单可作为一种指示,那么在当代轿车、卡车和跨界车的引擎盖下面正发生一场静悄悄的革命。涡轮增压、机械增压和柴油引擎——甚至还有一款电动发电机——主导了第20届年度十大最佳汽车引擎奖;根据《沃兹汽车》,这些奖项“表彰了杰出的动力系统成就、世界级技术以及那些帮助推动汽车销售的稀有发动机或者电力推进系统。”
7. Smart cookie oven
中国旅游研究院国际旅游研究所(Institute of International Tourism)副所长蒋依依认为,外国游客数量下降的部分原因在于人民币的升值。
2016年,中国电影票房经历了一次令人震惊的调整,从2015年的48%大幅下降到3.7%。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

通用汽车现在已经对挥泪大促销上瘾,新首席执行长惠塔克里(Ed Whitacre)对此心知肚明。他将在2010年取消一些购买刺激措施,以放弃全美20%市场占有率目标的方式来谋求重获盈利能力。这番求索注定是前路艰难。
另一种看法是,油价在过去三年中的变动,是长期结构性变化的开始,预示着下一个50年里,能源价格按实际值计算将显著低于上一个50年。简单地说,持这种看法的人认为,供给的增长潜力超过需求增长。
泰国董里岛——董里岛是泰国东南部一个可被雷达侦测到的沉睡之省,游人可以在那里租长尾船,到岛屿之间穿行,还可以去看濒临灭绝的儒艮。
一位不具名的北京癌症专家23日称,虽说破坏科学公信力的行为不该有任何借口,但是这起事件揭示了中国医生面临的普遍困境,即在超负荷的日常工作安排与发表论文以争取职业发展和升职的主要学术要求之间很难维持平衡。
Despite the breakthrough, Jack Ma, chairman of Alibaba Group, said there was no need for human beings to fear machines.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

单词deputy 联想记忆:
另一个出人意料的新领域是纳米技术。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

中国和越南的关系因中国南海领土问题而变得日益紧张。两国媒体都对这一事件进行了报道,指责各自政府将非法食品投放本国市场。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Do you routinely roll your eyes? Do you have a weak handshake? Do you avoid making eye contact? These could all be career killers. People must understand that actions speak louder than words. And the majority of our communication is done through non-verbal cues. People could perceive some of your non-verbal communication habits as rude or unprofessional—and these things could eventually have a significant impact on the advancement of your career.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

During the RoboCup 2500 contestants from 40 countries competed in 15 competitions with various types of computerized soccer robots, healthcare robots, rescue robots and dance robots.
Last year, the CPI increase peaked at 2.5 percent in January, and later fluctuated below 2 percent during the rest of the year.
Based on a new estimate provided by the government of Dubai, its visitor spending of $31.3 billion this year far exceeds London's estimated $19.8 billion, which comes second.
她说,零售业务“起步不久,好坏参半”。她表示,亚太所有国家都有大量工作要做,并补充称,澳大利亚的事例证明,就吸引散户兴趣而言,监管改变可以带来显著不同。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Apple CEO Tim Cook
时间:2010-05-17 编辑:francie
Since you will be spending so much time in your office space, you should be comfortable enough to enjoy what you do. A comfy chair will keep you pleased throughout the day. We recommend the Allak Swivel Chair, $59.99, at Ikea.com. If you need music to keep your mind stirring, we recommend the Sound System iPod Speaker, $220, at UrbanOutfiters.com.
Allianz

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
From the themed collection: 整装市场下的卫浴行业新趋势
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

这让11月份的贸易顺差达到446.1亿美元,比10月份减少约44.5亿美元,低于预期。
5. Google Webmaster Tools.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

The booming Internet economy now is playing an increasingly important role in supporting wealth growth in China's IT industry.
The first selfie stick was invented long before the first handheld mobile device was made. A selfie stick was definitely invented by the Japanese man Hiroshi Ueda in the 1980s. A photographer and worker at the Minolta camera company, Hiroshi made the selfie stick because he and his wife were unable to take pictures of themselves during a trip to Europe. (When he asked a boy to take pictures of them, the boy ran off with the camera.)
像中国人口这么多的国家,关于寂寞的病毒式模仿会这么流行实在是件很讽刺的事情。这句看上去很无厘头的话被用在了所有可能搭配的排列中,用在了所有场合,比如,“哥看的不是书,是寂寞。”
艾丽斯·斯瓦策尔(Alice Schwarzer)
全食CEO约翰麦基的《自觉资本主义》(Conscious Capitalism)一书让公司高管们不得不思考这样一个观点,那就是处于最佳运转状态的企业能为所有利益相关方创造价值,而不仅仅是投资者。麦基认为,主要利益相关方包括顾客、员工、供应商、社会以及环境。他以好市多、西南航空(Southwest Airlines ,《财富》500强)和谷歌(Google,《财富》500强)为例,说明思维超越利润能够打造更强大而、更高效的公司。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

11. 《黑豹党:革命先锋》(The Black Panthers: Vanguard of the Revolution),导演:斯坦利?尼尔森(Stanley Nelson)。
The big winners over the past year in Arizona were the construction and leisure/hospitality industries, which both added more than 10, 000 jobs. Other fast-growing sectors include business services, financial activities and education and health services.
被氦气顶起来的泡沫穿过图形模板。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 晨阳水漆亮相纽约时代广场
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

根据中国海关总署(General Administration of Customs)发布的数据,12月份以美元计的出口额同比减少6.1%至2094.2亿美元。这一跌幅比经济学家预期的中数多了2.1个百分点,也大于11月份修正后1.6%的跌幅(修正前该数字为增长0.1%)。
眼下,合格的供应链经理极度缺乏,在那些分支机构遍布全球的跨国公司中尤其如此。究其原因,不外以下两点。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

8. Smile every time EXCEPT when my team is losing.
And, at random, some other highlights from the list:
这位工作人员说道:“她注册时说自己姓韩,也不是像媒体上报道的姓苏。”

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

With Westbrook playing such a hands-on, high-usage role and Victor Oladipo already locked in on a high-dollar extension, Payne needed to prove he could be an off-ball threat or a lead guard on the second unit.
4. Smart trashcan
中国仍然是世界经济复苏乏力情况下推动全球增长的重要力量。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

谎言7:没错,约翰昨晚是和我在一起。说谎原因:这就是朋友该做的事。等下我们两个还要通通气,以免穿帮。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 广州一手房成交创今年来新低
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

当瑞秋布鲁姆听闻自己赢得喜剧类电视最佳女主角奖项时,喜极而泣。亚马逊节目《丛林中的莫扎特》也意外斩获最佳剧集奖项。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

美联储上个月公布了今年放缓购债步伐的时间表。美联储计划在每一次政策会议上将购债规模减少100亿美元,直到今年年底不再进行购债。自从2012年末以来,美联储每个月都买入850亿美元美国国债和住房抵押贷款支持证券。
The computer is a very powerful machine built with ARM processors, the kind low-power processors that run smartphones and tablets. These servers allow more computing power o be packed into a smaller space. And that has big implications for building green-but-powerful data centers."I think of myself as an entrepreneur besides just being an electrical engineer. I believe what I'm doing can have a major effective on the world," Sohmers said.He dropped out of high school to join Peter Thiel's controversial startup accelerator, the 20 Under 20 Thiel Fellowship. Thiel, the former PayPal CEO and famous Silicon Valley venture capitalist known for his early investment in Facebook, is a libertarian who has often spoken out about the absurd cost of college these days.So in 2011, he started a program that encourages kids to start companies instead of going to college. It gives them $100,000 in seed money and access to some of the Valley's greatest technologists as mentors.Sohmers is an electrical engineering prodigy who at age 13 started working at the research lab at MIT. That's where he met his co-founder and CTO, Keville, he said.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

肥皂剧通常都在电视收视排行榜上位居前列,但2012最流行的电视节目是英国广播电台儿童节目《麦克小骑士》,它打败了美国惊悚电视剧《国土安全》和真人秀节目《Towie》。
[ri'septiv]
汇丰发布的正式PMI指数从10月份的50.4降至11月份的50.0,这是6个月内的最低读数。
Happy new year, my best friend.祝我的挚友新年快乐。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

NeXT 电脑公司总裁兼CEO史蒂夫乔布斯在向公众展示他的新一代NeXT 工作站(此时乔布斯已经离开苹果创办了皮克斯动画和NeXT 电脑公司),1990年9月18日,旧金山
添加方式2.搜索微信号ikekenet添加即可。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

野村证券(Nomura)的分析师表示:“我们预期这一轮出口增长的反弹不会维持很长时间,未来数月增长势头将恢复温和,原因是人民币的升值可能弱化中国的出口竞争力,且即使习主席和特朗普总统近期在北京会面,发生贸易摩擦的潜在风险并未显著减轻。”
4.The Mask Of Zorro

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Ahead of the release, economists at ANZ said they expected inflation to pick up in January owing to rising food prices, and the low commodity prices would weigh on the CPI.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

创造就业和削减赤字将成为华盛顿在2010年选举之年的孪生执念。不过,这两样一个都成不了现实。
麦迪逊马里奇(Madison Marriage)是会计和税收事务记者
吊床架
卡尔森一向热衷于歌唱事业和歌剧事业,因而这样的工作对她再合适不过了。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

When it comes to diversity, I am optimistic that at some point the rise of enlightened younger executives will trigger a sudden change of attitude in the boardroom. This will not happen in 2018, though the imbalances and abuses of power evident in sexual harassment scandals, from tech to media, could accelerate change.
沿海江苏省的无锡市以4.9%的环比涨幅连续第二个月处于首位。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

n. 精美的东西
时间:2011-11-03 编辑:Lily
'I think South Korea has a very rigorous and narrow definition of beauty because we’re an ethnically homogenous society and everyone looks pretty much the same. It is also related to low self-esteem.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

报告提供了对除北京和上海之外的28个国内商业和行政中心城市进行的深入考察。
optimistic
大部分原因还是全球变暖,而全球变暖主要是二氧化碳排放量上升造成的。二氧化碳是主要的人为温室气体,通过燃烧煤、石油等化石燃料产生。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Swyft有50家短信应用合作伙伴,包括Kakao Talk, Facebook Messenger, BlackBerry Messenger和 Line。这种合作让这家只有11个人的小公司能接触到25亿注册用户。随着利用短信应用赚钱的办法不断演化,这家年轻的创业公司已探索出一条可让各大品牌挤进人们聊天领域的生财之道。(财富中文网)
n. 饰带,花边,缎带

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 扶养独居老人者可适当继承遗产
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

在被问及欧洲央行会不会采取更多行动时,朗伯德街研究(Lombard Street Research)首席欧洲经济学家达里奥·铂金斯(Dario Perkins)表示:“我不这么认为——除非全球整体经济出了问题。”
You know the old guy who's been at the company forever and still can't figure out email? If you don't get up to speed on social media in 2014, you'll be that guy. Compared to last year, there are 13 times as many jobs advertised on Indeed.com that mention the use of social media. "We are seeing an increased demand for social savvy candidates across the business -- from human resources to product to customer service, " Amy Crow, Indeed's communication director told Quartz earlier this year. Not only are departments like marketing, sales, and customer service expected to be on Twitter (TWTR) and Facebook, teams as diverse as R&D, logistics, and HR are increasingly using internal networks like Yammer to streamline operations. Social media has grown so critical to the workplace, in fact, that major universities are beginning to offer certificate programs for socially inept corporate types to get up to speed.
The immediacy for a larger-screen iPhone comes partially from the Asian market where Samsung’s phablets have made significant inroads. Assuming that Apple’s agreement with China Mobile includes these upcoming products, the pricing adjustments that normally occur with new iPhones could make the iPhone 5C significantly more affordable and attractive to the Chinese market. This would begin to make sense of the 5C, which so far seems to be a sales disappointment for Apple. Perhaps the important thing about the 5C is that it is not the 5S, so that down the road it can be discounted without putting price pressure on Apple’s flagship.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

The pair stand on opposite sides backstage and memorize the winners to avoid having to write them down and have revealed in the past how they carry out rigorous checks to ensure they have stuffed the envelopes correctly. It is believed Ruiz and Cullinan are ordered to destroy the duplicate cards as the presentation goes on, so by the time Best Picture is awarded, the only envelopes left are the two for Best Picture.
Gitanjali因为拿下了本次最高奖项,从而获得了一笔2.5万美元的奖金。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

汇丰发布的正式PMI指数从10月份的50.4降至11月份的50.0,这是6个月内的最低读数。
“为什么这件事发生在我女儿身上?”她说,“因为枪支造成的死亡太多了,我不知道还要死多少人。”
Second, McDermott, a career 39.9% three-point shooter, addresses Oklahoma City's biggest roster weakness—a lack of perimeter options around Russell Westbrook—and remains on a bargain rookie deal through the end of next season.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

1. Hokkaido, Japan-Though known primarily to the outside world for its ski resorts and powdery snow, Hokkaido's year-round beauty might soon become a more familiar sight to foreign visitors. The new bullet-train service from Tokyo should help.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

中国旅游研究院国际旅游研究所(Institute of International Tourism)副所长蒋依依认为,外国游客数量下降的部分原因在于人民币的升值。
卡利南和瑞兹各提一只装着所有奖项结果信封的手提箱——也就是说,每个奖项都有两只信封。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

受能源和大宗商品价格日益下跌影响,中国12月工业生产者出厂价格连续第34个月下跌。
《火线警探》,FX,1月20日。副警长瑞兰·吉文斯(Raylan Givens,蒂莫西·奥利芬特[Timothy Olyphant]饰)与他的朋友兼天敌博伊德·克劳达(Boyd Crowder,沃尔顿·戈金斯[Walton Goggins]饰)之间爱恨交织的关系贯穿了整部剧,不管怎样,这个问题将在第六季,也就是最终季中得到最终解决。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 广州100套房源已开放出租
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

今年2月的时候,玛蒂参加了J.Mendel2015秋冬高级成衣发布秀(图)
According to the study, 75% of consumers are aware of wearable technology (whether as futuristic fashion or new-age tech tool), but only 9% actually have any interest in wearing it. A meager 2% admitted to owning a wearable tech device, most of which consist of fitness trackers and smart watches, according to the study.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

10.自拍杆
清华大学是国内表现最好的大学,有三项学科的排名进入全球前10。北京大学则是有两项学科排名挤入前十。就清华大学而言,建筑/建成环境和土木/结构工程学均排名第8,材料科学排名第10。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

2011年,在《老友记》最后一季播出7年之后,美国卫星电视频道Comedy Central再次播放该剧,观看人数超过了3600万,而观众的年龄主要分布在16岁至34岁之间。假期时,看剧人数更是由于播放集数增加而飙升。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Barney Thompson is legal correspondent
2、说谎
Thirty-six Chinese brands have made it onto the list this year. Among them, eight are in the top 100, including the State Grid Corporation of China (36), the Industrial and Commercial Bank of China (ICBC) (40), Tencent (43), China Central Television (CCTV) (62), Haier (76), China Mobile (79), Huawei (81) and Lenovo (90).
不会。事情可能会这样发展:在一次试运营(其间出现多次交易停止)后,比特币期货将慢慢开始吸引机构资金。美国商品期货交易委员会(CFTC)的持仓数据将反映出资金管理公司对该产品存在的长期偏见。随着减仓的巨额成本变得不言自明,多头将越来越大声地抱怨围绕结算时间的例行分歧。就在参议院计划举行听证会调查潜在的市场操纵行为时,比特币期货价格将跌破现货价格,引发抛售。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 家具市场定制热2016年持续升温
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Intel welcomes its new employees to the company by rolling out the red carpet -- literally -- once a quarter. During the first day of orientation, hires walk along a pathway lined with Intel Studios' photographers and videographers before introducing themselves onstage and receiving their welcome packages (and a round of applause from an audience of new colleagues).

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Although no North American cities feature in the top 20, the EIU said the cost of living in New York had risen relative to other places in the United States. It shares 27th position as the most expensive US city with Los Angeles.
Elsewhere, Stockholm School of Economics was a big winner, climbing 16 places to 28, not only recording the best year-on-year progression but also recovering from a drop of 11 places last year.
尽管中国国内经济放缓,中国对欧洲和美国的投资却达到创纪录高位。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

My hunch is that this draft will look pretty good by March and will be much better than last year's, which was one of the most underwhelming in recent memory. New Orleans and Washington both need some direction, and soon.
['m?:gid?]

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

The first wearable computer glasses were made by Edward Thorp and Claude Shannon in 1961. In 1968, Ivan Sutherland made the "Sword of Damocles." It was the first head-mounted computer display and an early variant of all wearable computer glasses we have today. In 1980, Steve Mann, known today as the father of wearable computing, made the "WearComp", a pair of tech-enhanced glasses that was capable of communicating wirelessly with other computers and could share videos. He continued to work on the glasses over the years, and by 1999, he had come up with a pair of glasses that looked like Google Glass, or rather, that Google Glass looks like. He called it the "EyeTap."
1号 what the fuck: “职场辣妈”的新境界

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

凯特·温斯莱特(Kate Winslet)是另一位将其最佳女演员奖杯置于洗手间的英国演员。她因在2008年一部改编自本哈德·施林克(Bernhard Schlink)的小说《生死朗读》(The Reader)的同名影片中扮演一位集中营的看守而获此殊荣。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 首次买房需要看四点
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Christie’s biannual evening sale on Dec. 8 raised just 6.5 million pounds with fees, about $9.7 million, against a low estimate of 12.7 million. Nineteen of the 45 works, or 42 percent, failed to sell, including the two most highly valued lots — a 1582 watercolor study of a hare among plants by Hans Hoffmann, a pupil of Albrecht Dürer, and a fine 1770s Francesco Guardi view of the island of San Giorgio Maggiore in Venice, carrying low estimates of 4 million and 1.5 million respectively.
First, says Tom Kozenski, a supply-chain expert at consulting and training firm RedPrairie, most people still think of logistics -- if they think of it at all -- as a "non-sexy" field centered on boring, low-paid warehouse work.
根据这份新报告,在过去20年里,印度是发起反倾销案最多的国家,在1995年至2015年间发起的4990件反倾销案中,印度发起了767件,占比为15%。同期,美国发起了570件,欧盟发起了480件。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Yet there are similarities between the demagogic elements of the Brexit campaign and the rise of Mr Trump.
它被广泛误解为一部关于小说家大卫·福斯特·华莱士(David Foster Wallace)的传记电影,其实庞索特的这部影片是一部关于新闻的坏方法的喜剧,以及对文学名誉机制充满了解的辛酸讽刺。杰西·艾森伯格(Jesse Eisenberg)与杰森·西格尔(Jason Segel)使用“男人老友电影”(buddy movie)的传统方式,完美地呈现出一个新的子类:亦敌亦友电影。
The incomes of graduates from universities listed in China's 211, or 985 key university national projects are far ahead of those from ordinary universities, the survey found.
一个解释是,在金融业高薪领域工作的男性比例远远超过女性比例。三分之一的男性在私募、风险资本、投资银行或者并购以及对冲基金领域工作,而女性只有19%。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

天蓝、地绿、水清的美丽中国
?Bond has a keen eye for who to trust and who not to. This quality is frequently seen in sexually open-minded people, actually. 007 can tell when a lady is into him. And science agrees: handsome men are the best at identifying who is attracted to them.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Currency movements have had a strong impact on agricultural commodity prices this year, with the UK’s referendum on the EU leading to a sharp fall in the pound that pushed up the price of food imports and boosted agricultural exports.
美国经济将会表现得更好就算世界上其他地区没能做到
这家瑞士学校在2016年全球90个最佳管理学硕士项目中荣登榜首,连续6年夺冠。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

桑尼伯恩说他不仅对特朗普的错误决定和无知时期感到失望,同时也因为总统对8月在弗吉尼亚州夏洛茨维尔举行的白人种族主义集会上反抗者被杀害后做出的回应感到失望——这也更加坚定了桑尼伯恩竞选州长的决心。
所有这些合数值都比去年同期高,其中市场价值增幅最大(比去年同期增长13%)。这些公司在全球总共雇用了9000万人。

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